LIQUID AND SEMI-SOLID Dosage FORMS

FLÜSSIGE UND HALBFESTE DARREICHUNGSFORMEN

Our wide range of dosage forms comprises liquid formulations, ointments, creams, pastes, lotions, gels and suppositories.

Liquid formulations

Our reactors with 500, 1,000, and 3,000 L capacities enable the production of solutions and suspensions under controlled conditions (temperature, pressure, inert gases).
This equipment can also be used to produce syrup or alcohol solutions as well as solid-containing suspensions.
The reactors are CIP-equipped (Clean-In-Place). Solutions can be filtered (up to 0.2 ㎛) before transfer to the filling area and direct supply to the filling unit.

Filling drop tubes – specific technology

Our filling line is qualified to fill liquid forms into drop tubes and bottles.

Suppositories

Vifor Pharma currently produces more than 20 million suppositories a year.
Batches of 90 to 250 kg are filled into plastic strips. The average weight per unit is scalable to 1-3 g/unit.
In order to ensure an error-free packaging process, the suppository strips are packaged into boxes under constant control (completeness, barcode scanner to check printed secondary packaging material).

Gels, ointments, creams, lotions

Semi-solid formulations can be produced with the following equipment:

  • 200 L homogeniser
  • Mixer-homogeniser with a capacity of 2000 L in accordance with ATEX requirements (non-explosive atmosphere)

Filling into plastic or aluminium tubes

  • Ø 16 to 35 mm
  • Height 50 to 175 mm (without cap) 
  • Batch number and expiry date may be embossed or printed on the tube.
  • Our filling line for tubes of semi-solid and liquid forms enables us to achieve high filling speeds.

Enemas

A special plant controls the production of solutions and suspensions (up to 900 L). The enemas are filled (30 to 60 mL), sealed and labelled.
Enemas can be blistered under inert gas in order to improve the stability of the solution.
The enemas and leaflets are packaged into boxes (containing up to 21 units) directly at the plant. The folding boxes can also be imprinted.

Contact

Vifor Ltd.

Contract Development & Manufacturing
Route de Moncor 10
P.O. Box
CH-1752 Villars-sur-Glâne

Phone:
+41 58 851 61 11
Fax:
+41 58 851 60 50

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